Principal Investigator
















Jorge N. Artaza



Artaza JN, Sirad F, Ferrini MG, Norris KC. 1,25(OH)2 vitamin D3 inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells. Journal of Steroid Biochemistry and Molecular Biology 2010;119:73-83. PMCID: PMC2828517

Sirad F, Hlaing S, Kovanecz I, Artaza JN, Garcia LA, Rajfer J, Ferrini MG. Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat. Journal of Sexual Medicine 2011;8:1048-1060. PMCID:



Artaza JN, Contreras S, Garcia LA, Mehrotra R, Gibbons G, Shohet R, Martins D, Norris KC. Vitamin D and cardiovascular disease: potential role in health disparities. Journal of Health Care for the Poor and Underserved 2011;22:23-38. PMCID: PMC3417128


Garcia LA, King KK, Ferrini MG, Norris KC, Artaza JN. 1,25(OH)2 Vitamin D3 stimulates myogenic differentiation by inhibiting cell proliferation and modulating the expression of promyogenic growth factors and myostatin in C2C12 skeletal muscle cells. Endocrinology 2011;152:2976-2986. PMCID: PMC3138228


Garcia LA, Ferrini MG, Norris KC, Artaza JN. 1,25(OH)(2) vitamin D(3) enhances myogenic differentiation by modulating the expression of key angiogenic growth factors and angiogenic inhibitors in C(2)C(12) skeletal muscle cells. Journal of Steroid Biochemistry and Molecular Biology 2013;133:1-11. PMCID: PMC3513642


Hlaing SM, Garcia LA, Kovanecz I, Martinez RA, Shah S, Artaza JN, Ferrini MG. Sildenafil promotes neuroprotection of the pelvic ganglia neurones after bilateral cavernosal nerve resection in the rat. BJU International 2013;111:159-170. PMCID: PMC3548048


Martins D, Meng YX, Tareen N, Artaza J, Lee JE, Farodolu C, Gibbons G, Norris K. The Effect of Short Term Vitamin D Supplementation on the Inflammatory and Oxidative Mediators of Arterial Stiffness.   Health (Irvine Calif). 2014 Jun;6(12):1503-1511. PMCID: PMC4260399


Hlaing SM, Garcia LA, Contreras JR, Norris KC, Ferrini MG, Artaza JN. 1,25-Vitamin D3 promotes cardiac differentiation through modulation of the WNT signaling pathway.

J Mol Endocrinol. 2014 Dec;53(3):303-17. doi: 10.1530/JME-14-0168. Epub 2014 Aug 19.PMID: 25139490 PMCID: 4198487


Garcia LA, Hlaing SM, Gutierrez RA, Sanchez MD, Kovanecz I, Artaza JN, Ferrini MG.

Sildenafil attenuates inflammation and oxidative stress in pelvic ganglia neurons after bilateral cavernosal nerve damage. Int J Mol Sci. 2014 Sep 26;15(10):17204-20. doi: 10.3390/ijms151017204. PMID: 25264738 PMCID: PMC4227157


Aaron T. Ohta


Hu W, Fan Q, Ishii KS, Ohta AT. An optically controlled 3D cell culturing system. Advances in Optoelectronics 2011 Jan 1;2011. pii: 253989. Epub 2011 Sep 12. PMCID: PMC3373019.
Qiyi Tang


Cosme-Cruz R, Martinez FP, Perez KJ, Tang Q. H2B homology region of major immediate-early protein 1 is essential for murine cytomegalovirus to disrupt nuclear domain 10, but is not important for viral replication in cell culture. Journal of General Virology 2011;92:2006-2019. PMCID: PMC3353387

Cosme-Cruz R, Martinez FP, Tang Q. Functional interaction of nuclear domain 10 and its components with cytomegalovirus after infections: cross-species host cells versus native cells. PLoS One 2011;6:e19187. PMCID: PMC3084273


Martinez FP, Tang Q. Leucine zipper domain is required for Kaposi sarcoma-associated herpesvirus (KSHV) K-bZIP protein to interact with histone deacetylase and is important for KSHV replication. Journal of Biological Chemistry 2012;287:15622-15634. PMCID: PMC3346108


Rivera-Molina YA, Rojas BR, Tang Q. Nuclear domain 10-associated proteins recognize and segregate intranuclear DNA/protein complexes to negate gene expression. Virology Journal 2012;9:222. PMCID: PMC3502357


Perez KJ, Martínez FP, Cosme-Cruz R, Perez-Crespo NM, Tang Q. A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replication. Journal of Virology 2013;87:2639-47. PMCID: PMC3571397


Selariu A, Cheng T, Tang Q, Silver B, Yang L, Liu C, Ye X, Markus A, Goldstein RS, Cruz-Cosme RS, Lin Y, Wen L, Qian H, Han J, Dulal K, Huang Y, Li Y, Xia N, Zhu H. ORF7 of varicella-zoster virus is a neurotropic factor. Journal of Virology 2012;86:8614-8624. PMCID: PMC3421744


Martínez FP, Tang Q. Identification of cellular proteins that interact with human cytomegalovirus immediate-early protein 1 by protein array assay. Viruses. 2013 Dec 31;6(1):89-105. PubMed PMID: 24385082; PubMed Central PMCID: PMC3917433.


Tang Q, Roan NR, Yamamura Y. Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture. J Virol. 2013 Dec;87(23):12583-91. doi:

10.1128/JVI.02083-13. Epub 2013 Sep 11. PMID:24027327; PMCID: PMC3838150


Rivera-Molina YA, Martínez FP, Tang Q. Nuclear domain 10 of the viral aspect. World J Virol. 2013 Aug 12;2(3):110-22. PubMed PMID:24255882; PubMed Central PMCID: PMC3832855.


Martínez FP, Cruz R, Lu F, Plasschaert R, Deng Z, Rivera-Molina YA, Bartolomei MS, Lieberman PM, Tang Q. CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication.J Virol. 2014 Jul;88(13):7389-401. doi: 10.1128/JVI.00845-14. Epub 2014 Apr 16. PMID: 24741094 PMCID: PMC 4054410


Torres L, Ortiz T, Tang Q. Enhancement of herpes simplex virus (HSV) infection by seminal plasma and semen amyloids implicates a new target for the prevention of HSV infection.Viruses. 2015 Apr 20;7(4):2057-73. doi: 10.3390/v7042057.PMID:25903833 PMCID: PMC4411690


Sheba George


George S, Moran E, Duran N, Jenders RA. Using animation as an information tool to advance health research literacy among minority participants. AMIA Annu Symp Proc. 2013 Nov 16;2013:475-484. eCollection 2013. PMID: 24551351; PMCID: PMC3900192 

George S, Duran N, Norris K. A systematic review of barriers and facilitators to minority   research participation among African Americans, Latinos, Asian Americans, and Pacific Islanders. Am J Public Health. 2014 Feb;104(2):e16-31. PubMed PMID: 24328648. PMCID: PMC3935672


Antonio Martins


Martins AH, Hu J, Xu Z, Mu C, Alvarez P, Ford BD, El Sayed K, Eterovic VA, Ferchmin PA, Hao J. Neuroprotective activity of (1S,2E,4R,6R,-7E,11E)-2,7,11-cembratriene-4,6-diol (4R) in vitro and in vivo in rodent models of brain ischemia. Neuroscience. 2015 Apr 16;291:250-9. doi: 10.1016/j.neuroscience.2015.02.001. Epub 2015 Feb 10. PMID:25677097 PMCID: PMC4369428


Ferchmin PA, Andino M, Reyes Salaman R, Alves J, Velez-Roman J, Cuadrado B, Carrasco M, Torres-Rivera W, Segarra A, Martins AH, Lee JE, Eterovic VA. 4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration.

Neurotoxicology. 2014 Sep;44:80-90. doi: 10.1016/j.neuro.2014.06.001. Epub 2014 Jun 10. PMID: 24928201 PMCID: PMC176603


Valerie Wonja   UPR Agsalda-Garcia M, Shiramizu B, Melendez L, Plaud M, Liang CY, Wojna V. Different levels of HIV DNA copy numbers in cerebrospinal fluid cellular subsets. J Health Care Poor Underserved. 2013 Nov;24(4 Suppl):8-16. doi: 10.1353/hpu.2014.0010.PubMed PMID: 24241256 PMCID: PMC3844931
2010 Anthony Archibong


Archibong AE, Ramesh A, Inyang F, Niaz MS, Hood DB, Kopsombut P. Endocrine disruptive actions of inhaled benzo(a)pyrene on ovarian function and fetal survival in fisher F-344 adult rats. Reproductive Toxicology 2012;34:635-643. PMCID: PMC3513493
Katilyn Csiszar


Laczko R, Szauter KM, Csiszar K, LOXL1-associated candidate epithelial pathomechanisms in exfoliation glaucoma. J Glaucoma. 2014 Oct-Nov;23(8 Suppl 1):S43-7. doi: 10.1097/IJG.0000000000000105. PMID: 25275905 PMCID: PMC4205763
Robert DottinHunter



Fleming ES, Perkins J, Easa D, Conde JG, Baker RS, Southerland WM, Dottin R, Benabe JE, Ofili EO, Bond VC, McClure SA, Sayre MH,,Beanan MJ, Norris KC. Addressing health disparities through multiinstitutional,,multidisciplinary collaboratories. Ethn Dis. 2008,Spring;18(2 Suppl 2):S2-161-7. PubMed PMID: 18646341; PubMedCentral PMCID: PMC2705198.


Fleming ES, Perkins J, Easa D, Conde JG, Baker RS, Southerland WM, Dottin R, Benabe JE, Ofili EO, Bond VC, McClure SA, Sayre MH, Beanan MJ, Norris KC. The role of translational research in addressing health disparities: a conceptual framework. Ethnic Dis. 2008 Spring;18(2 Suppl 2):S2-155-60. PubMed PMID: 18646340; PubMed Central PMCID: PMC2705204.


Ana M. Espino


Caban-Hernandez K, Gaudier JF, Espino AM. Characterization and differential expression of a ferritin protein from Fasciola hepatica. Molecular and Biochemical Parasitology 2012;182:54-61. PMCID: PMC3277670

Figueroa-Santiago O, Delgado B, Espino AM. Fasciola hepatica saposin-like protein-2-based ELISA for the serodiagnosis of chronic human fascioliasis. Diagnostic Microbiology and Infectious Disease 2011;70:355-361. PMCID: PMC3260655


Gaudier JF, Caban-Hernandez K, Osuna A, Espino AM. Biochemical characterization and differential expression of a 16.5-kilodalton tegument-associated antigen from the liver fluke Fasciola hepatica. Clinical and Vaccine Immunology 2012;19:325-333. PMCID: PMC3294618


Morales A, Espino AM. Evaluation and characterization of Fasciola hepatica tegument protein extract for serodiagnosis of human fascioliasis. Clinical and Vaccine Immunology 2012;19:1870-1878. PMCID: PMC3491547


Xinbin Gu



Zhang Y, Barnes AN, Zhu X, Campbell NF, Gao R. Quantification of thiopurine/UVA-induced singlet oxygen production. Journal of Photochemistry and Photobiology 2011;224:16-24. PMCID: PMC3210580

Li W, Lu W, Fan Z, Zhu X, Reed A, Newton B, Zhang Y, Courtney S, Tiyyagura PT, Li S, Butler E, Yu H, Ray PC, Gao R. Enhanced photodynamic selectivity of nano-silica-attached porphyrins against breast cancer cells. Journal of Materials Chemistry 2012;22:12701-12708. PMCID: PMC3501744


Aggarwal A, Thompson S, Singh S, Newton B, Moore A, Gao R, Gu X, Mukherjee S, Drain CM. Photophysics of Glycosylated Derivatives of a Chlorin, Isobacteriochlorin and Bacteriochlorin for Photodynamic Theragnostics: Discovery of a Two-photon-absorbing Photosensitizer. Photochem Photobiol. 2013 Oct 1;PubMed PMID: 24112086; PMCID: PMC3959241


William E. Haskins


Raphael I, Mahesula S, Kalsaria K, Kotagiri V, Purkar AB, Anjanappa M, Shah D, Pericherla V, Jadhav YL, Raghunathan R, Vaynberg M, Noriega D, Grimaldo NH, Wenk C, Gelfond JA, Forsthuber TG, Haskins WE. Microwave and magnetic (M(2) ) proteomics of the experimental autoimmune encephalomyelitis animal model of multiple sclerosis. Electrophoresis 2012;33:3810-3819. PMCID: PMC3703760

Mahesula S, Raphael I, Raghunathan R, Kalsaria K, Kotagiri V, Purkar AB, Anjanappa M, Shah D, Pericherla V, Jadhav YL, Gelfond JA, Forsthuber TG, Haskins   WE. Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Electrophoresis. 2012 Dec;33(24):3820-9. doi: 10.1002/elps.201200515. PMID: 23160929; PMCID: PMC3724470.


Raphael I, Mahesula S, Purkar A, Black D, Catala A, Gelfond JA, Forsthuber TG, Haskins WE. Microwave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis.

Sci Rep. 2014 Sep 3;4:6210. doi: 10.1038/srep06210. PMID:25182730 PMCID:PMC4152753


Evans TM, Van Remmen H, Purkar A, Mahesula S, Gelfond JA, Sabia M, Qi W, Lin AL, Jaramillo CA, Haskins WE. Microwave & Magnetic (M2) Proteomics of a Mouse Model of Mild Traumatic Brain Injury. Transl Proteom. 2014 Jun 1;3:10-21. PMID: 26157646 PMCID: PMC4492171


Mandip Sachdeva


Patel AR, Chougule MB, I T, Patlolla R, Wang G, Singh M. Efficacy of aerosolized celecoxib encapsulated nanostructured lipid carrier in non-small cell lung cancer in combination with docetaxel. Pharmaceutical Research 2013;30:1435-1446. PMCID: PMC3618607
Suwit Somponpun


Somponpun SJ, Wong B, Hynd TE, Fogelgren B, Lozanoff S. Osmoregulatory defect in adult mice associated with deficient prenatal expression of six2. American Journal of Physiology, Regulatory, Integrative and Comparative Physiology 2011;301:R682-R689. PMCID: PMC3174753
Asikiya Walcourt


Sana TR, Gordon DB, Fischer SM, Tichy SE, Kitagawa N, Lai C, Gosnell WL, Chang SP. Global mass spectrometry based metabolomics profiling of erythrocytes infected with Plasmodium falciparum. PLoS One 2013;8:e60840. PMCID: PMC3621881
2011 Jun Panee



Higa JK, Liang Z, Williams PG, Panee J. Phyllostachys edulis compounds inhibit palmitic acid-induced monocyte chemoattractant protein 1 (MCP-1) production. PLoS One 2012;7(9):e45082. PMCID: PMC3445604

Panee J. Monocyte chemoattractant protein 1 (MCP-1) in obesity and diabetes. Cytokine 2012;60:1-12. PMCID: PMC3437929


Higa JK, Liu W, Berry MJ, Panee J. Supplement of bamboo extract lowers serum monocyte chemoattractant protein-1 concentration in mice fed a high fat diet. British Journal of Nutrition 106:1810–1813, 2011. PMCID: PMC3437929


Cedomir Todorovic


Murthy SR, Sherrin T, Jansen C, Nijholt I, Robles M, Dolga AM, Andreotti N, Sabatier JM, Knaus HG, Penner R, Todorovic C, Blank T. Small-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory. PLoS One. 2015 May 4;10(5):e0127264. doi: 10.1371/journal.pone.0127264. eCollection 2015.PMID: 25938421 PMCID: PMC4418695 

Lawrence JL, Tong M, Alfulaij N, Sherrin T, Contarino M, White MM, Bellinger FP, Todorovic C, Nichols RA. Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment. J Neurosci. 2014 Oct 22;34(43):14210-8. doi: 10.1523/JNEUROSCI.0326-14.2014. PMID: 25339735 PMCID: PMC4205547


Huan Xie


Xie H, Goins B, Bao A, Zheng Wang J, Phillips WT. Effects of intra-tumoral administration on bio-distribution of 64Cu-labeled nanoshells. International Journal of Nanomedicine. 2012;7:2227–2238. PMCID: PMC3356223 

Liang S, Bian X, Ma J, Arogunjo M, Deorukhkar AA, Krishnan S, Xie H. Development and validation of a sensitive LC/MS/MS method for the determination of γ-tocotrienol in rat plasma: application to pharmacokinetic studies. Biomedical Chromatography 2013;27:58-66. PMCID: PMC3696499


Liang S, Bian X, Sivils J, Neckers LM, Cox MB, Xie H. Quantification of a New Anti-Cancer Molecule MJC13 Using a Rapid, Sensitive, and Reliable Liquid Chromatography-Tandem Mass Spectrometry Method.Am J Mod Chromatogr. 2014;1(1):1-11.PMID:25594071 PMCID: PMC4292881




Suranganie Dharmawardhane UPR Castillo-Pichardo L, Humphries-Bickley T, De La Parra C, Forestier-Roman I,Martinez-Ferrer M, Hernandez E Vlaar C, Ferrer-Acosta Y, Washington A, Cubano L, Rodriguez-Orengo J, Dharmawardhane S. The Rac inhibitor EHop-016 Inhibits Mammary Tumor Growth And Metastasis In A Nude Mouse Model Translational Oncology   PMID: 25389450 [PubMed] PMCID: PMC4225654 .


Humphries-Bickley, T, Castillo-Pichardo, L, Corujo-Carro, F, Duconge, J, Hernandez-O’Farrill, E, Vlaar,C, Rodriguez-Orengo, J, Cubano, L, and Dharmawardhane , S. Pharmacokinetics of Rac Inhibitor EHop-016 in Mice by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry. 2015, , Journal Chromatography B, PMCID: PMC4306626


Lily Cheung


Cheung LK, Lal LS, Chow DS, Sherman V. Racial disparity in short-term outcomes after gastric bypass surgery. Obes Surg 2013; 23: 2096-2103. PMCID No. 23868139
2014 Wonsuk Yoo


Yoo W, Mayberry R, Bae S, He Q, Singh K. A Study of Effects of Multicollinearity in the Multivariable Analysis. International Journal of Applied Science and Technology, 2014;4(5):9-19. PMID: 25664257, PMCID: PMC4318006.
Pablo Vivas-Mejia


Echevarría-Vargas IM, Valiyeva F, Vivas-Mejía PE. Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway. PLoS One. 2014 May 27;9(5):e97094. doi: 10.1371/journal.pone.0097094. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e116447. PMID: 24865582 PMCID: PMC4035252.

Rivera-Díaz M, Miranda-Román MA, Soto D, Quintero-Aguilo M, Ortiz-Zuazaga H, Marcos-Martinez MJ, Vivas-Mejía PE. MicroRNA-27a distinguishes glioblastoma multiforme from diffuse and anaplastic astrocytomas and has prognostic value.Am J Cancer Res. 2014 Dec 15;5(1):201-18. eCollection 2015.PMID:25628931 PMCID: PMC4030691.


Wen Y, Graybill WS, Previs RA, Hu W, Ivan C, Mangala LS, Zand B, Nick AM, Jennings NB, Dalton HJ, Sehgal V, Ram P, Lee JS, Vivas-Mejia PE, Coleman RL, Sood AK.

Immunotherapy targeting folate receptor induces cell death associated with autophagy in ovarian cancer.Clin Cancer Res. 2015 Jan 15;21(2):448-59. doi: 10.1158/1078-0432.CCR-14-1578. Epub 2014 Nov 21.PMID:25416196 PMCID: PMC4297546.



Y. Meng, D. Martins, N. Tareen, J. Liu, J. Lee, D. Sarpong, G. Gibbons, KC Norris. VITAMIN D SUPPLEMENTATION AND VASCULAR FUNCTION IN AFRICAN AMERICANS. 13th RCMI International Symposium on Health Disparities, San Juan, PR. December 10-13, 2012.

Y. Meng, D. Martins, N. Tareen, J. Liu, J. Lee, D. Sarpong, G. Gibbons, KC Norris. SAFETY OF HIGH DOSE VITAMIN D SUPPLEMENTATION IN AFRICAN AMERICANS. 13th RCMI International Symposium on Health Disparities, San Juan, PR. December 10-13, 2012.


D. Martins, Y. Meng, N. Tareen, J. Liu, J. Atarza, J. Lee, G. Gibbons, KC Norris. An optimum vitamin D dosing schedule for overweight and obese African-American adults with vitamin D deficiency. (submitted to Journal of National Medical Association)

D. Martins, Y. Meng, N. Tareen, J. Artaza, J. Lee, C. Farodolu, G. Gibbons and KC Norris. The Effect of Short-term Vitamin D Supplementation on the Inflammatory and Oxidative Mediators of Arterial Stiffness (drafted out for submission to Journal of American Medical Association)